Join Microsoft’s Peter Lee on a journey to discover how AI is impacting healthcare and what it means for the future of medicine.
Two years ago, OpenAI’s GPT-4 kick-started a new era in AI. In the months leading up to its public release, Peter Lee, president of Microsoft Research, cowrote The AI Revolution in Medicine: GPT-4 and Beyond, a book full of optimism for the potential of advanced AI models to transform the world of healthcare. What has happened since? In this special Microsoft Research Podcast series, Lee revisits the book, exploring how patients, providers, and other medical professionals are experiencing and using generative AI today while examining what he and his coauthors got right—and what they didn’t foresee.
“’I think that Zak and his mother deserve better than that.’ I was being scolded. And while I’ve been scolded plenty in my life, for the first time it wasn’t a person scolding me; it was an artificial intelligence system.”
– Peter Lee, “Chapter 1: First Contact,” The AI Revolution in Medicine: GPT-4 and Beyond
Episodes
The AI Revolution in Medicine, Revisited: An Introduction
Peter Lee talks about his early encounters with GPT-4, when the AI model was still in secret development with OpenAI, and the range of emotions he cycled through as he came to understand the new technology better. The emergence of generative AI has created a “new world,” Lee says, one he is eager to investigate with the aim of discovering the technology’s impact so far and what it means for the future of healthcare and medicine.
Episode 1 | The reality of generative AI in the clinic
Dr. Christopher Longhurst, Dr. Sara Murray | March 20, 2025
UC San Diego Health’s Dr. Christopher Longhurst and UC San Francisco Health’s Dr. Sara Murray explore how generative AI is changing patient care, clinical workflows, and decision-making and how they envision the technology impacting the future of healthcare.
Guests
Dr. Sara Murray (opens in new tab)
Dr. Sara Murray is the chief health AI officer at UC San Francisco Health and an associate professor of clinical medicine.
Dr. Christopher Longhurst (opens in new tab)
Dr. Christopher Longhurst is the chief clinical and innovation officer at UC San Diego Health and a professor of medicine and pediatrics.
Episode 2 | Real-world healthcare AI development and deployment—at scale
Dr. Matthew Lungren, Seth Hain | April 3, 2025
Microsoft’s Dr. Matthew Lungren and Epic’s Seth Hain discuss the challenges and opportunities of leveraging generative AI for enhanced patient care and improved clinical documentation and recordkeeping at scale—plus what’s next for the technology in the field.
Guests
Dr. Matthew Lungren
Dr. Matthew Lungren is the chief scientific officer at Microsoft Health and Life Sciences, where he focuses on translating cutting-edge technology into innovative healthcare applications.
Seth Hain (opens in new tab)
Seth Hain is the senior vice president of R&D at the healthcare software company Epic. He focuses on AI, analytics, and more across the company’s healthcare applications.
Episode 3 | Empowering patients and healthcare consumers in the age of generative AI
Dave deBronkart, Christina Farr | April 17, 2025
Evangelist for patient empowerment Dave deBronkart and Manatt Heath’s Christina Farr discuss how generative AI is redefining healthcare by empowering patients, challenging traditional care models, and creating new opportunities for innovation and collaboration.
Guests
Dave deBronkart (opens in new tab)
Dave deBronkart, known online as “e-Patient Dave,” is author of the book Let Patients Help! and one of the world’s leading advocates for patient empowerment.
Christina Farr (opens in new tab)
Christina Farr is a managing director at the consulting firm Manatt. She also runs a newsletter called Second Opinion and a fund called Scrub Capital.
Up next
Episode 4
Dr. Roxana Daneshjou, Laura Adams, Vardit Ravitsky | May 1, 2025
Series contributors: Neeltje Berger, Tetiana Bukhinska, David Celis Garcia, Matt Corwine, Kristina Dodge, Chris Duryee, Ben Ericson, Kate Forster, Alyssa Hughes, Jake Knapp, Weishung Liu, Matthew McGinley, Amanda Melfi, Wil Morrill, Joe Plummer, Brenda Potts, Amber Tingle, Craig Tuschoff, and Katie Zoller.